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Anticancer Research|September 27, 2015
The In Vitro and In Vivo Activity of the Microtubule Disruptor STX140 Is Mediated by Hif-1 Alpha and CAIX ExpressionChloe Stengel, Simon P Newman, Mathew P Leese, et al.Molecular and Cellular Endocrinology|February 24, 2006
17Beta-hydroxysteroid dehydrogenase Type 1 and Type 2: association between mRNA expression and activity in cell linesJoanna M Day, Helena J Tutill, Simon P Newman, et al.Journal of Medicinal Chemistry|March 16, 2010
Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamateFabrice Jourdan, Mathew P Leese, Wolfgang Dohle, et al.Chemmedchem|October 13, 2011
Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495)L W Lawrence Woo, Dharshini Ganeshapillai, Mark P Thomas, et al.Biochemical and Biophysical Research Communications|March 30, 2004
2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitorJulie E Reed, L W Lawrence Woo, James J Robinson, et al.The Biochemical Journal|September 30, 2004
Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agentMatthew D Lloyd, Richard L Pederick, Ramanathan Natesh, et al.Chemmedchem|September 26, 2008
Synthesis of aromatase inhibitors and dual aromatase steroid sulfatase inhibitors by linking an arylsulfamate motif to 4-(4H-1,2,4-triazol-4-ylamino)benzonitrile: SAR, crystal structures, in vitro and in vivo activitiesChristian Bubert, L W Lawrence Woo, Oliver B Sutcliffe, et al.Breast Cancer Research and Treatment|October 25, 2007
2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo techniquePaul A Foster, Yaik T Ho, Simon P Newman, et al.Journal of Medicinal Chemistry|April 15, 2005
Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitorsHarshani R Lawrence, Nigel Vicker, Gillian M Allan, et al.Journal of Medicinal Chemistry|June 22, 2007
Dual aromatase-steroid sulfatase inhibitorsL W Lawrence Woo, Christian Bubert, Oliver B Sutcliffe, et al.Pageof 9