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ACS Medicinal Chemistry Letters|October 23, 2018
Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1Autumn R Flynn, Suzanne G Mays, Eric A Ortlund, et al.
Journal of the American Chemical Society|May 8, 2020
Hydroarylation of Arenes via Reductive Radical-Polar CrossoverAutumn R Flynn, Kelly A McDaniel, Meredith E Hughes, et al.
ACS Medicinal Chemistry Letters|March 19, 2020
Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear ReceptorsEmma H D'Agostino, Autumn R Flynn, Jeffery L Cornelison, et al.
Journal of the American Chemical Society|August 2, 2023
Using Data Science for Mechanistic Insights and Selectivity Predictions in a Non-Natural Biocatalytic ReactionHanna D Clements, Autumn R Flynn, Bryce T Nicholls, et al.
The Journal of Biological Chemistry|October 4, 2016
Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic AgonistsSuzanne G Mays, C Denise Okafor, Richard J Whitby, et al.
The Journal of Biological Chemistry|June 16, 2023
Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulatorsMichael L Cato, Emma H D'Agostino, Racheal M Spurlin, et al.
Journal of Medicinal Chemistry|May 3, 2022
Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding PocketMichael L Cato, Jeffery L Cornelison, Racheal M Spurlin, et al.
Journal of Medicinal Chemistry|August 17, 2019
Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided DesignSuzanne G Mays, Autumn R Flynn, Jeffery L Cornelison, et al.
Cell Chemical Biology|March 22, 2022
A phospholipid mimetic targeting LRH-1 ameliorates colitisSuzanne G Mays, Emma H D'Agostino, Autumn R Flynn, et al.
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