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Nature Genetics
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January 3, 2024
Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications
Áine Duffy, Ben Omega Petrazzini, David Stein, et al.
Cancer Discovery
|
February 11, 2021
Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling
Christos Adamopoulos, Tamer A Ahmed, Maxwell R Tucker, et al.
Nature Communications
|
September 24, 2020
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity
J G Coen van Hasselt, Rayees Rahman, Jens Hansen, et al.
Nucleic Acids Research
|
November 25, 2010
ModBase, a database of annotated comparative protein structure models, and associated resources
Ursula Pieper, Benjamin M Webb, David T Barkan, et al.
Journal of Medicinal Chemistry
|
July 27, 2018
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)
Huan-Chieh Chien, Claire Colas, Karissa Finke, et al.
Plos Computational Biology
|
September 14, 2021
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
Zhaoping Xiong, Minji Jeon, Robert J Allaway, et al.
Annals of Neurology
|
January 13, 2019
SLC13A3 variants cause acute reversible leukoencephalopathy and α-ketoglutarate accumulation
Joseph P Dewulf, Elsa Wiame, Imen Dorboz, et al.
Nature Structural & Molecular Biology
|
February 6, 2013
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome
Ursula Pieper, Avner Schlessinger, Edda Kloppmann, et al.
American Journal of Human Genetics
|
May 23, 2024
Haploinsufficiency underlies the neurodevelopmental consequences of SLC6A1 variants
Dina Buitrago Silva, Marena Trinidad, Alicia Ljungdahl, et al.
Science Translational Medicine
|
February 11, 2021
Human neurons from Christianson syndrome iPSCs reveal mutation-specific responses to rescue strategies
Sofia B Lizarraga, Li Ma, Abbie M Maguire, et al.
Page
of 12
Search research articles
Search
Showing results (101-110 of 118) with videos related to
Sort By:
Page
of 12
Nature Genetics
|
January 3, 2024
Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications
Áine Duffy, Ben Omega Petrazzini, David Stein, et al.
Cancer Discovery
|
February 11, 2021
Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling
Christos Adamopoulos, Tamer A Ahmed, Maxwell R Tucker, et al.
Nature Communications
|
September 24, 2020
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity
J G Coen van Hasselt, Rayees Rahman, Jens Hansen, et al.
Nucleic Acids Research
|
November 25, 2010
ModBase, a database of annotated comparative protein structure models, and associated resources
Ursula Pieper, Benjamin M Webb, David T Barkan, et al.
Journal of Medicinal Chemistry
|
July 27, 2018
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)
Huan-Chieh Chien, Claire Colas, Karissa Finke, et al.
Plos Computational Biology
|
September 14, 2021
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
Zhaoping Xiong, Minji Jeon, Robert J Allaway, et al.
Annals of Neurology
|
January 13, 2019
SLC13A3 variants cause acute reversible leukoencephalopathy and α-ketoglutarate accumulation
Joseph P Dewulf, Elsa Wiame, Imen Dorboz, et al.
Nature Structural & Molecular Biology
|
February 6, 2013
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome
Ursula Pieper, Avner Schlessinger, Edda Kloppmann, et al.
American Journal of Human Genetics
|
May 23, 2024
Haploinsufficiency underlies the neurodevelopmental consequences of SLC6A1 variants
Dina Buitrago Silva, Marena Trinidad, Alicia Ljungdahl, et al.
Science Translational Medicine
|
February 11, 2021
Human neurons from Christianson syndrome iPSCs reveal mutation-specific responses to rescue strategies
Sofia B Lizarraga, Li Ma, Abbie M Maguire, et al.
Page
of 12