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International Journal of Clinical Pharmacology and Therapeutics|October 25, 2013
Application of population pharmacokinetic modeling to explore the impact of alternative roflumilast dosing regimens on tolerabilityGezim Lahu, Axel Facius
Combinatorial Chemistry & High Throughput Screening|February 14, 2006
Bioinformatics challenges in proteomicsClaudia C Englbrecht, Axel Facius
Clinical Pharmacokinetics|May 26, 2018
Pharmacokinetic and Pharmacodynamic Modelling to Characterize the Tolerability of Alternative Up-Titration Regimens of Roflumilast in Patients with Chronic Obstructive Pulmonary DiseaseAxel Facius, Eleonora Marostica, Philip Gardiner, et al.
Journal of Clinical Pharmacology|April 19, 2017
Modeling and Simulation of Pivotal Clinical Trials Using Linked Models for Multiple Endpoints in Chronic Obstructive Pulmonary Disease With RoflumilastAxel Facius, Andreas Krause, Laurent Claret, et al.
International Journal of Clinical Pharmacology and Therapeutics|April 25, 2013
An innovative phase I population pharmacokinetic approach to investigate the pharmacokinetics of an intranasal fentanyl spray in healthy subjectsNele Plock, Axel Facius, Lene Hartmann, et al.
International Journal of Clinical Pharmacology and Therapeutics|July 13, 2012
Population pharmacokinetic meta-analysis of intranasal fentanyl spray as a means to enrich pharmacokinetic information for patients with cancer breakthrough painNele Kaessner, Rüdiger Nave, Stefan Roepcke, et al.
BMC Bioinformatics|April 5, 2005
Super paramagnetic clustering of protein sequencesIgor V Tetko, Axel Facius, Andreas Ruepp, et al.
Clinical and Translational Science|March 6, 2024
Population pharmacokinetics, enzyme occupancy, and pharmacodynamic modeling of soticlestat in patients with developmental and epileptic encephalopathiesWei Yin, Axel Facius, Mahnaz Asgharnejad, et al.
International Journal of Clinical Pharmacology and Therapeutics|July 29, 2014
Utility of a population pharmacokinetic meta analysis during the approval process of teduglutide for the treatment of short bowel syndromeStefan Roepcke, Ruediger Nave, Jane Cyran, et al.
Clinical and Translational Science|May 22, 2023
Population pharmacokinetics, enzyme occupancy, and 24S-hydroxycholesterol modeling of soticlestat, a novel cholesterol 24-hydroxylase inhibitor, in healthy adultsWei Yin, Axel Facius, Thomas Wagner, et al.
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