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Science Signaling|November 25, 2025
SOS1 inhibition suppresses the emergence of osimertinib resistance to generate a durable response in EGFR-mutant lung cancerBrianna R Daley, Patricia L Theard, Jacob M Hughes, et al.
Immunology and Cell Biology|June 17, 2022
SATB1 ensures appropriate transcriptional programs within naïve CD8+ T cellsSimone Nüssing, Lisa A Miosge, Kah Lee, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 13, 2014
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cellsJohn A Altin, Stephen R Daley, Jason Howitt, et al.
European Journal of Immunology|May 7, 2021
c-Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in miceThomas S Fulford, Raelene Grumont, Rushika C Wirasinha, et al.
The Journal of Allergy and Clinical Immunology|August 13, 2021
Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitutionOttavia M Delmonte, Riccardo Castagnoli, Jason Yu, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 16, 2023
SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation statusBrianna R Daley, Heidi M Vieira, Chaitra Rao, et al.
Nature Immunology|June 13, 2025
Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cellsElisabetta Petrozziello, Amina Sayed, João A Freitas, et al.
Cancer Research|October 22, 2024
SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung AdenocarcinomaBrianna R Daley, Nancy E Sealover, Bridget A Finniff, et al.
Elife|December 17, 2013
Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodiesStephen R Daley, Kristen M Coakley, Daniel Y Hu, et al.
The Journal of Experimental Medicine|October 27, 2020
Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibilityRushika C Wirasinha, Ainsley R Davies, Monika Srivastava, et al.
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