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Biochemistry|February 18, 2026
Rational Design of Plant-Derived Protein Ligases with Altered Substrate SpecificityYan Zhou, Simon J de Veer, Tristan J Tyler, et al.Science (New York, N.Y.)|January 25, 2024
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coliRongzhen Tian, Fabian B H Rehm, Dariusz Czernecki, et al.ACS Chemical Biology|June 15, 2021
Asparaginyl Ligase-Catalyzed One-Step Cell Surface Modification of Red Blood CellsThibault J Harmand, Novalia Pishesha, Fabian B H Rehm, et al.Proceedings of the National Academy of Sciences of the United States of America|April 5, 2019
Papain-like cysteine proteases prepare plant cyclic peptide precursors for cyclizationFabian B H Rehm, Mark A Jackson, Ewout De Geyter, et al.Journal of the American Chemical Society|June 11, 2025
Asparaginyl Ligases with Engineered Substrate Specificity for Controlled, Sequential Transpeptidation ReactionsYan Zhou, Simon J de Veer, Tristan J Tyler, et al.Nucleic Acids Research|January 29, 2025
An evolved, orthogonal ssDNA generator for targeted hypermutation of multiple genomic lociWeiran Chu, Rongzhen Tian, Yaxin Guo, et al.Nature Chemistry|May 24, 2024
Repurposing a plant peptide cyclase for targeted lysine acylationFabian B H Rehm, Tristan J Tyler, Yan Zhou, et al.Nature Communications|March 30, 2020
A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitorsJunqiao Du, Kuok Yap, Lai Yue Chan, et al.Angewandte Chemie (International Ed. in English)|February 28, 2022
Cystine Knot Peptides with Tuneable Activity and MechanismChoi Yi Li, Fabian B H Rehm, Kuok Yap, et al.Nature Protocols|February 18, 2021
Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidasesKuok Yap, Junqiao Du, Fabian B H Rehm, et al.Pageof 6