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The Journal of Pharmacology and Experimental Therapeutics|February 9, 2017
Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac FibroblastsKatherine B Schuetze, Matthew S Stratton, Weston W Blakeslee, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 24, 2014
Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibitionSama F Sleiman, David E Olson, Megan W Bourassa, et al.
Neuroscience Letters|July 2, 2013
FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitorsFrederick A Schroeder, Daniel B Chonde, Misha M Riley, et al.
ACS Chemical Neuroscience|September 5, 2014
PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in ratF A Schroeder, C Wang, G C Van de Bittner, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 22, 2012
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cellsStefan Kubicek, Joshua C Gilbert, Dina Fomina-Yadlin, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|March 11, 2011
AKT kinase activity is required for lithium to modulate mood-related behaviors in miceJen Q Pan, Michael C Lewis, Josh K Ketterman, et al.
Bioorganic & Medicinal Chemistry|July 6, 2016
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitorsFlorence F Wagner, Michel Weïwer, Stefan Steinbacher, et al.
Plos One|August 23, 2013
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related testsFrederick A Schroeder, Michael C Lewis, Daniel M Fass, et al.
Science Translational Medicine|May 22, 2020
Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndromePatrick K McCamphill, Laura J Stoppel, Rebecca K Senter, et al.
Scientific Reports|April 28, 2021
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injuryDavid D Aufhauser, Paul Hernandez, Seth J Concors, et al.
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