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Bioorganic & Medicinal Chemistry Letters|October 10, 2001
1,3,4-Trisubstituted pyrrolidine CCR5 receptor antagonists. Part 2: lead optimization affording selective, orally bioavailable compounds with potent anti-HIV activityJ J Hale, R J Budhu, E B Holson, et al.
Cancer Cell|November 16, 2010
Hdac3 is essential for the maintenance of chromatin structure and genome stabilitySrividya Bhaskara, Sarah K Knutson, Guochun Jiang, et al.
ACS Chemical Biology|December 8, 2015
An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell ProtectionFlorence F Wagner, Morten Lundh, Taner Kaya, et al.
ACS Chemical Biology|August 5, 2014
An unbiased approach to identify endogenous substrates of "histone" deacetylase 8David E Olson, Namrata D Udeshi, Noah A Wolfson, et al.
Chemical Science|February 3, 2015
Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition EnhancersF F Wagner, Y-L Zhang, D M Fass, et al.
Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids|May 4, 2019
2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 diseaseJessica Davidson, Elizabeth Molitor, Samantha Moores, et al.
The Journal of Organic Chemistry|August 3, 2012
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like librariesJason T Lowe, Maurice D Lee, Lakshmi B Akella, et al.
ACS Chemical Biology|February 28, 2018
Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic TreatmentMichel Weïwer, Qihong Xu, Jennifer P Gale, et al.
Science Translational Medicine|March 9, 2018
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemiaFlorence F Wagner, Lina Benajiba, Arthur J Campbell, et al.
ACS Chemical Biology|April 30, 2016
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional EffectsFlorence F Wagner, Joshua A Bishop, Jennifer P Gale, et al.
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