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Alzheimer'S Research & Therapy|May 25, 2012
Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brainsBrenda D Moore, Paramita Chakrabarty, Yona Levites, et al.The Journal of Biological Chemistry|October 9, 2012
Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP)Hyo-Jin Park, Daniil Shabashvili, Michael D Nekorchuk, et al.Journal of Neurochemistry|November 23, 2005
Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42Stefanie Leuchtenberger, Markus P Kummer, Thomas Kukar, et al.Cell Reports|May 3, 2019
APP-Mediated Signaling Prevents Memory Decline in Alzheimer's Disease Mouse ModelCarole Deyts, Mary Clutter, Nicholas Pierce, et al.EMBO Molecular Medicine|October 21, 2018
High-affinity interactions and signal transduction between Aβ oligomers and TREM2Christian B Lessard, Samuel L Malnik, Yingyue Zhou, et al.Journal of Medicinal Chemistry|November 28, 2012
Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteasesYanxia Liu, Wei Zhang, Li Li, et al.ASN Neuro|June 8, 2021
Aspergillus versicolor Inhalation Triggers Neuroimmune, Glial, and Neuropeptide Transcriptional ChangesThatcher B Ladd, James A Johnson, Christen L Mumaw, et al.The Journal of Biological Chemistry|April 23, 2008
Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretaseEva Czirr, Barbara A Cottrell, Stefanie Leuchtenberger, et al.Molecular Neurodegeneration|July 15, 2015
Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulatorJoo In Jung, Ashleigh R Price, Thomas B Ladd, et al.The Journal of Biological Chemistry|August 27, 2011
Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane regionThomas L Kukar, Thomas B Ladd, Paul Robertson, et al.Pageof 5