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Journal of Medicinal Chemistry
|
October 25, 2016
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction
Andreas Gollner, Dorothea Rudolph, Heribert Arnhof, et al.
Oncotarget
|
March 18, 2020
Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis
Stefanie Schlager, Carina Salomon, Sabine Olt, et al.
Journal of Medicinal Chemistry
|
February 12, 2019
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
Johannes Popow, Heribert Arnhof, Gerd Bader, et al.
Molecular Cancer Therapeutics
|
February 7, 2020
Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance
Marco H Hofmann, Rajeswaran Mani, Harald Engelhardt, et al.
Nature
|
May 31, 2023
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth
Dongsung Kim, Lorenz Herdeis, Dorothea Rudolph, et al.
Journal of Medicinal Chemistry
|
October 27, 2022
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS<sup>G12C</sup> Inhibitor
Joachim Bröker, Alex G Waterson, Chris Smethurst, et al.
Journal of Medicinal Chemistry
|
September 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
Timothy R Hodges, Jason R Abbott, Andrew J Little, et al.
Chemmedchem
|
December 4, 2020
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based Methods
Dirk Kessler, Moriz Mayer, Stephan K Zahn, et al.
Communications Chemistry
|
January 19, 2026
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
Nishma Gupta, Nicole Trainor, Mona Radwan, et al.
Nature Communications
|
April 14, 2025
Drugit: crowd-sourcing molecular design of non-peptidic VHL binders
Thomas Scott, Christian Alan Paul Smethurst, Yvonne Westermaier, et al.
Page
of 24
Search research articles
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Showing results (211-220 of 234) with videos related to
Sort By:
Page
of 24
Journal of Medicinal Chemistry
|
October 25, 2016
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction
Andreas Gollner, Dorothea Rudolph, Heribert Arnhof, et al.
Oncotarget
|
March 18, 2020
Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis
Stefanie Schlager, Carina Salomon, Sabine Olt, et al.
Journal of Medicinal Chemistry
|
February 12, 2019
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
Johannes Popow, Heribert Arnhof, Gerd Bader, et al.
Molecular Cancer Therapeutics
|
February 7, 2020
Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance
Marco H Hofmann, Rajeswaran Mani, Harald Engelhardt, et al.
Nature
|
May 31, 2023
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth
Dongsung Kim, Lorenz Herdeis, Dorothea Rudolph, et al.
Journal of Medicinal Chemistry
|
October 27, 2022
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS<sup>G12C</sup> Inhibitor
Joachim Bröker, Alex G Waterson, Chris Smethurst, et al.
Journal of Medicinal Chemistry
|
September 12, 2018
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
Timothy R Hodges, Jason R Abbott, Andrew J Little, et al.
Chemmedchem
|
December 4, 2020
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based Methods
Dirk Kessler, Moriz Mayer, Stephan K Zahn, et al.
Communications Chemistry
|
January 19, 2026
Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
Nishma Gupta, Nicole Trainor, Mona Radwan, et al.
Nature Communications
|
April 14, 2025
Drugit: crowd-sourcing molecular design of non-peptidic VHL binders
Thomas Scott, Christian Alan Paul Smethurst, Yvonne Westermaier, et al.
Page
of 24