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Proceedings of the National Academy of Sciences of the United States of America
|
May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1
David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 26, 2003
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues
Raj N Misra, Hai yun Xiao, David B Rawlins, et al.
Molecular Pharmacology
|
November 3, 2016
Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics
J Daniel Hothersall, Dong Guo, Sunil Sarda, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 20, 2003
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases
Raj N Misra, David B Rawlins, Hai-yun Xiao, et al.
Nucleic Acids Research
|
January 29, 2021
Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition
Tom E H Ogden, Ji-Chun Yang, Marianne Schimpl, et al.
ACS Chemical Biology
|
September 17, 2019
Rapid Identification of Novel Allosteric PRC2 Inhibitors
Jon A Read, Jonathan Tart, Philip B Rawlins, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
October 30, 2016
Unified Software Solution for Efficient SPR Data Analysis in Drug Research
Göran Dahl, Stephan Steigele, Per Hillertz, et al.
Archives of Toxicology
|
January 1, 2022
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment
Gregory Hamm, Gareth Maglennon, Beth Williamson, et al.
Pharmacology Research & Perspectives
|
June 4, 2015
LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2
David R Powell, Melinda G Smith, Deon D Doree, et al.
RSC Medicinal Chemistry
|
November 3, 2022
Fragment screening at AstraZeneca: developing the next generation biophysics fragment set
Simon C C Lucas, Ulf Börjesson, Mark J Bostock, et al.
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of 5
Search research articles
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Showing results (21-30 of 50) with videos related to
Sort By:
Page
of 5
Proceedings of the National Academy of Sciences of the United States of America
|
May 15, 2023
Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1
David Hargreaves, Rodrigo J Carbajo, Michael S Bodnarchuk, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 26, 2003
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues
Raj N Misra, Hai yun Xiao, David B Rawlins, et al.
Molecular Pharmacology
|
November 3, 2016
Structure-Activity Relationships of the Sustained Effects of Adenosine A2A Receptor Agonists Driven by Slow Dissociation Kinetics
J Daniel Hothersall, Dong Guo, Sunil Sarda, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 20, 2003
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases
Raj N Misra, David B Rawlins, Hai-yun Xiao, et al.
Nucleic Acids Research
|
January 29, 2021
Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition
Tom E H Ogden, Ji-Chun Yang, Marianne Schimpl, et al.
ACS Chemical Biology
|
September 17, 2019
Rapid Identification of Novel Allosteric PRC2 Inhibitors
Jon A Read, Jonathan Tart, Philip B Rawlins, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
October 30, 2016
Unified Software Solution for Efficient SPR Data Analysis in Drug Research
Göran Dahl, Stephan Steigele, Per Hillertz, et al.
Archives of Toxicology
|
January 1, 2022
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment
Gregory Hamm, Gareth Maglennon, Beth Williamson, et al.
Pharmacology Research & Perspectives
|
June 4, 2015
LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2
David R Powell, Melinda G Smith, Deon D Doree, et al.
RSC Medicinal Chemistry
|
November 3, 2022
Fragment screening at AstraZeneca: developing the next generation biophysics fragment set
Simon C C Lucas, Ulf Börjesson, Mark J Bostock, et al.
Page
of 5