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Clinical Pharmacology and Therapeutics|April 19, 2017
Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical TrialsD M Longo, G T Generaux, B A Howell, et al.
Pharmacogenetics|December 12, 2001
In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentrationY S Lin, G F Lockwood, M A Graham, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 14, 2017
miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture ModelMerrie Mosedale, J Scott Eaddy, O Joseph Trask, et al.
Clinical and Translational Science|June 8, 2018
Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology ModelingJeffrey L Woodhead, Franziska Paech, Martina Maurer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 4, 1999
Molecular and physical mechanisms of first-pass extractionS D Hall, K E Thummel, P B Watkins, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 29, 2015
FutureTox II: in vitro data and in silico models for predictive toxicologyThomas B Knudsen, Douglas A Keller, Miriam Sander, et al.
Hepatology (Baltimore, Md.)|November 18, 2009
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylationRick D Fannin, Mark Russo, Thomas M O'Connell, et al.
Pharmacology Research & Perspectives|October 19, 2019
Quantitative systems toxicology (QST) reproduces species differences in PF-04895162 liver safety due to combined mitochondrial and bile acid toxicityGrant Generaux, Vinal V Lakhani, Yuching Yang, et al.
Nature Communications|September 2, 2021
Carbon clusters formed from shocked benzeneD M Dattelbaum, E B Watkins, M A Firestone, et al.
Physics in Medicine and Biology|October 9, 2007
A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeriesMariya Lazebnik, Dijana Popovic, Leah McCartney, et al.
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