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The Journal of Clinical Investigation|February 17, 2026
Galectin-3 mediates lysosome-related inflammation within monocyte-derived macrophages in a mouse model of ischemic brain injuryMiao Wang, Zhentai Huang, Zhihong Du, et al.The Journal of Biological Chemistry|December 12, 2001
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalitiesBabak Razani, Terry P Combs, Xiao Bo Wang, et al.Molecular Biology of the Cell|March 13, 2003
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic miceTerence M Williams, Michelle W-C Cheung, David S Park, et al.Frontiers in Nutrition|June 18, 2025
Assessing the efficacy of the natural disaccharide trehalose in ameliorating diet-induced obesity and metabolic dysfunctionYu-Sheng Yeh, Trent D Evans, Se-Jin Jeong, et al.Immunity|August 7, 2021
Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stressRysa Zaman, Homaira Hamidzada, Crystal Kantores, et al.Autophagy|August 31, 2017
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathwayHaiyan Liu, Ali Javaheri, Rebecca J Godar, et al.Arteriosclerosis, Thrombosis, and Vascular Biology|September 9, 2017
CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief ReportHanrui Zhang, Jianting Shi, Melanie A Hachet, et al.The Journal of Experimental Medicine|November 9, 2021
Neutrophil DREAM promotes neutrophil recruitment in vascular inflammationJing Li, Tripti Kumari, Andrew Barazia, et al.Cell Metabolism|August 7, 2012
Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesityIrfan J Lodhi, Li Yin, Anne P L Jensen-Urstad, et al.Autophagy|March 12, 2021
Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis responseSe-Jin Jeong, Jeremiah Stitham, Trent D Evans, et al.Pageof 11