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Bioorganic & Medicinal Chemistry Letters|December 28, 2018
Development of novel liver X receptor modulators based on a 1,2,4-triazole scaffoldShaimaa S Goher, Kristine Griffett, Lamees Hegazy, et al.International Journal of Biological Macromolecules|March 18, 2026
Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signalingHazem Essam Okda, Puhan Zhao, Matt Hayes, et al.Bioorganic Chemistry|December 19, 2021
Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activityMahmoud A Ragab, Mohamed Elagawany, Hoda Daabees, et al.Bioorganic Chemistry|July 20, 2020
Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonistsMohamed Shahien, Mohamed Elagawany, Sadichha Sitaula, et al.Journal of Medicinal Chemistry|June 25, 2026
Discovery of Imine-Modified Quinazolinyl Sulfonamides as Dual hCA IX/XII Inhibitors with Potent Antiproliferative ActivityHazem Essam Okda, Lingaiah Maram, Mohammad Homaidur Rahman, et al.ACS Chemical Biology|April 13, 2022
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse AgonistsKristine Griffett, Matthew Hayes, Gonzalo Bedia-Diaz, et al.Nature Communications|November 22, 2022
Structural basis of synthetic agonist activation of the nuclear receptor REV-ERBMeghan H Murray, Aurore Cecile Valfort, Thomas Koelblen, et al.Journal of Medicinal Chemistry|December 23, 2025
Discovery of BE2012, a First-in-Class REV-ERBα/β Antagonist with Favorable Selectivity and Pharmacokinetics, and In Vivo Efficacy in Inducing Key Myogenic Factors for Muscle Repair upon Acute Muscle InjuryLingaiah Maram, Aurore-Cecile Valfort, Mohammad Homaidur Rahman, et al.European Journal of Medicinal Chemistry|December 21, 2024
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrierLingaiah Maram, Jessica M Michael, Henry Politte, et al.Pharmacological Reviews|November 25, 2025
Edaravone: Advances on cytoprotective effects, pharmacological properties, and mechanisms of actionFatima Dakroub, Bassel Awada, Samar Abdelhady, et al.Pageof 5