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Journal of Biopharmaceutical Statistics|June 22, 2013
The joint modeling of drug and positive control effects to estimate sample size and power in crossover "thorough" QT/QTc studiesBalakrishna Hosmane, Charles Locke, Yi-Lin Chiu
Journal of Biopharmaceutical Statistics|April 2, 2010
Sample size and power estimation in "thorough" QT/QTc studies with parallel group designBalakrishna Hosmane, Charles Locke, Yi-Lin Chiu
Journal of Biopharmaceutical Statistics|April 2, 2010
Exposure-response modeling approach for assessing QT effect in "thorough" QT/QTc studiesBalakrishna Hosmane, Charles Locke, Yi-Lin Chiu
Journal of Biopharmaceutical Statistics|June 22, 2013
Crossover versus parallel designs: dose-escalation design comparisons for first-in-human studiesZhiwu Yan, Balakrishna Hosmane, Charles Locke
Journal of Biopharmaceutical Statistics|July 5, 2021
Drug response hysteresis in the concentration-QTc analysis of early clinical trialsHong Li, Bo Tong, Balakrishna Hosmane, et al.
Journal of Biopharmaceutical Statistics|November 19, 2025
Blinded sample size re-estimation in a crossover studyShaofei Zhao, Balakrishna Hosmane, Chen Chen, et al.
Cancer Chemotherapy and Pharmacology|November 19, 2013
Results of a phase I, open-label, randomized, crossover study evaluating the effects of linifanib on QTc intervals in patients with solid tumorsYi-Lin Chiu, Patricia Lorusso, Balakrishna Hosmane, et al.
Clinical Pharmacology and Therapeutics|August 2, 2017
Use of Early Clinical Trial Data to Support Thorough QT Study Waiver for Upadacitinib and Utility of Food Effect to Demonstrate ECG Assay SensitivityMohamed-Eslam F Mohamed, Jiewei Zeng, Ping Jiang, et al.
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