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Balkrishen Bhat

Showing results (21-30 of 44) with videos related to

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Journal of Medicinal Chemistry|November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotidesPunit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
The Journal of Biological Chemistry|December 16, 2014
The microRNA-130/301 family controls vasoconstriction in pulmonary hypertensionThomas Bertero, Katherine Cottrill, Adrienn Krauszman, et al.
Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
The Journal of Organic Chemistry|February 9, 2010
Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analoguesPunit P Seth, Guillermo Vasquez, Charles A Allerson, et al.
Journal of Medicinal Chemistry|June 25, 2005
Positional effect of chemical modifications on short interference RNA activity in mammalian cellsThazha P Prakash, Charles R Allerson, Prasad Dande, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|October 31, 2021
Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expressionYanjie Li, Jixue Li, Jun Wang, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Nucleic Acids Research|May 5, 2017
Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Pageof 5

Showing results (21-30 of 44) with videos related to

Sort By:
Pageof 5
Journal of Medicinal Chemistry|November 10, 2010
Configuration of the 5'-methyl group modulates the biophysical and biological properties of locked nucleic acid (LNA) oligonucleotidesPunit P Seth, Charles R Allerson, Andrew Siwkowski, et al.
The Journal of Biological Chemistry|December 16, 2014
The microRNA-130/301 family controls vasoconstriction in pulmonary hypertensionThomas Bertero, Katherine Cottrill, Adrienn Krauszman, et al.
Journal of Medicinal Chemistry|January 30, 2010
Antisense oligonucleotides containing conformationally constrained 2',4'-(N-methoxy)aminomethylene and 2',4'-aminooxymethylene and 2'-O,4'-C-aminomethylene bridged nucleoside analogues show improved potency in animal modelsThazha P Prakash, Andrew Siwkowski, Charles R Allerson, et al.
The Journal of Organic Chemistry|February 9, 2010
Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analoguesPunit P Seth, Guillermo Vasquez, Charles A Allerson, et al.
Journal of Medicinal Chemistry|June 25, 2005
Positional effect of chemical modifications on short interference RNA activity in mammalian cellsThazha P Prakash, Charles R Allerson, Prasad Dande, et al.
Nucleic Acids Symposium Series (2004)|September 9, 2008
Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogsPunit P Seth, Andrew Siwkowski, Charles R Allerson, et al.
Nucleic Acids Research|October 31, 2021
Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expressionYanjie Li, Jixue Li, Jun Wang, et al.
Journal of the American Chemical Society|September 17, 2011
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotidesMartin Egli, Pradeep S Pallan, Charles R Allerson, et al.
Nucleic Acids Research|May 5, 2017
Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Nucleic Acids Research|March 11, 2015
Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activityThazha P Prakash, Walt F Lima, Heather M Murray, et al.
Pageof 5