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Molecular and Cellular Biology|August 19, 2015
Notch1 Autoactivation via Transcriptional Regulation of Furin, Which Sustains Notch1 Signaling by Processing Notch1-Activating Proteases ADAM10 and Membrane Type 1 Matrix MetalloproteinaseHong Qiu, Xiaoying Tang, Jun Ma, et al.
The Journal of Investigative Dermatology|March 12, 2016
Synchronized Targeting of Notch and ERBB Signaling Suppresses Melanoma Tumor Growth through Inhibition of Notch1 and ERBB3Keman Zhang, Poki Wong, Christine Salvaggio, et al.
Cancer Letters|July 24, 2018
Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive propertiesHong Qiu, Patrick M Zmina, Alex Y Huang, et al.
The Journal of Biological Chemistry|February 5, 2014
Noncanonical activation of Notch1 protein by membrane type 1 matrix metalloproteinase (MT1-MMP) controls melanoma cell proliferationJun Ma, Xiaoying Tang, Poki Wong, et al.
Pigment Cell & Melanoma Research|March 14, 2013
An ERBB3/ERBB2 oncogenic unit plays a key role in NRG1 signaling and melanoma cell growth and survivalKeman Zhang, Poki Wong, Jiaqi Duan, et al.
Plos One|July 8, 2021
MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restartVarsha Thakur, Juliano Tiburcio de Freitas, Yuan Li, et al.
Current Medicinal Chemistry|May 12, 2004
Mitochondrial superoxide dismutase: a promising target for new anticancer therapiesGiovambattista Pani, Renata Colavitti, Barbara Bedogni, et al.
The Journal of Clinical Investigation|October 18, 2008
Notch1 is an effector of Akt and hypoxia in melanoma developmentBarbara Bedogni, James A Warneke, Brian J Nickoloff, et al.
The Journal of Biological Chemistry|November 24, 2001
Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDRRenata Colavitti, Giovanni Pani, Barbara Bedogni, et al.
Pharmacological Research|October 1, 2016
The thiirane-based selective MT1-MMP/MMP2 inhibitor ND-322 reduces melanoma tumor growth and delays metastatic disseminationCharles Marusak, Ian Bayles, Jun Ma, et al.
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