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Chemical Research in Toxicology|November 13, 2020
In Silico Models to Predict the Perturbation of Molecular Initiating Events Related to Thyroid Hormone HomeostasisMarina Garcia de Lomana, Andreas Georg Weber, Barbara Birk, et al.Journal of Medicinal Chemistry|August 5, 2008
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivityRalf Heim, Simon Lucas, Cornelia M Grombein, et al.Journal of Medicinal Chemistry|October 17, 2009
New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: influence of additional substituents on 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitory activity and selectivityEmmanuel Bey, Sandrine Marchais-Oberwinkler, Matthias Negri, et al.Journal of Medicinal Chemistry|October 16, 2008
Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1)Emmanuel Bey, Sandrine Marchais-Oberwinkler, Ruth Werth, et al.Archives of Toxicology|September 4, 2023
Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoinSabina Ramirez-Hincapie, Barbara Birk, Philipp Ternes, et al.Archives of Toxicology|January 29, 2024
Molecular signatures of angiogenesis inhibitors: a single-embryo untargeted metabolomics approach in zebrafishPia Wilhelmi, Volker Haake, Franziska M Zickgraf, et al.Chemico-Biological Interactions|May 26, 2023
A metabolomics approach to reveal the mechanism of developmental toxicity in zebrafish embryos exposed to 6-propyl-2-thiouracilPia Wilhelmi, Varun Giri, Franziska Maria Zickgraf, et al.Toxicology Letters|October 9, 2021
Use of in vitro metabolomics in NRK cells to help predicting nephrotoxicity and differentiating the MoA of nephrotoxicantsBarbara Birk, Volker Haake, Saskia Sperber, et al.Cell Biology and Toxicology|May 3, 2023
A high-throughput metabolomics in vitro platform for the characterization of hepatotoxicitySabina Ramirez-Hincapie, Barbara Birk, Philipp Ternes, et al.ALTEX|June 11, 2020
The kinetic direct peptide reactivity assay (kDPRA): Intra- and inter-laboratory reproducibility in a seven-laboratory ring trialBritta Wareing, Susanne N Kolle, Barbara Birk, et al.Pageof 3