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Journal of Medicinal Chemistry|March 3, 2006
Synthesis and biological studies of a new series of 5-heteroarylcarbamoylaminopyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidines as human A3 adenosine receptor antagonists. Influence of the heteroaryl substituent on binding affinity and molecular modeling investigationsGiorgia Pastorin, Tatiana Da Ros, Chiara Bolcato, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|August 25, 2018
Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approachDelia Preti, Romeo Romagnoli, Riccardo Rondanin, et al.Journal of Medicinal Chemistry|September 19, 2003
Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigationGiorgia Pastorin, Tatiana Da Ros, Giampiero Spalluto, et al.Journal of Medicinal Chemistry|February 8, 2002
Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonistsPier Giovanni Baraldi, Barbara Cacciari, Stefano Moro, et al.Journal of Medicinal Chemistry|March 24, 2010
The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognitionSiew Lee Cheong, Anna Dolzhenko, Sonja Kachler, et al.Bioorganic & Medicinal Chemistry|June 9, 2009
Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sitesLisa Michielan, Chiara Bolcato, Stephanie Federico, et al.Bioorganic & Medicinal Chemistry|March 23, 2010
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition processGiorgia Pastorin, Stephanie Federico, Silvia Paoletta, et al.Bioorganic & Medicinal Chemistry|May 26, 2009
6-Amino-2-mercapto-3H-pyrimidin-4-one derivatives as new candidates for the antagonism at the P2Y12 receptorsPamela Crepaldi, Barbara Cacciari, Maria-Cruz Bonache, et al.Journal of Chemical Information and Modeling|May 28, 2013
Revisiting a receptor-based pharmacophore hypothesis for human A(2A) adenosine receptor antagonistsMagdalena Bacilieri, Antonella Ciancetta, Silvia Paoletta, et al.Molecules (Basel, Switzerland)|April 11, 2020
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine ScaffoldRomeo Romagnoli, Filippo Prencipe, Paola Oliva, et al.Pageof 5