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Organic & Biomolecular Chemistry|May 18, 2011
Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoeiSimona De Marino, Valentina Sepe, Maria Valeria D'Auria, et al.
Steroids|January 19, 2012
Polyhydroxylated sterols from the Indonesian soft coral Sinularia sp. and their effect on farnesoid X-activated receptorMasteria Yunovilsa Putra, Giorgio Bavestrello, Carlo Cerrano, et al.
European Journal of Pharmacology|August 3, 2011
Inhibition of NF-κB by a PXR-dependent pathway mediates counter-regulatory activities of rifaximin on innate immunity in intestinal epithelial cellsAndrea Mencarelli, Barbara Renga, Giuseppe Palladino, et al.
Scientific Reports|November 17, 2015
Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonismFrancesco Saverio Di Leva, Carmen Festa, Barbara Renga, et al.
European Journal of Pharmacology|December 10, 2013
In vivo administration of ritonavir worsens intestinal damage caused by cyclooxygease inhibitorsBarbara Renga, Andrea Mencarelli, Sabrina Cipriani, et al.
Plos One|November 3, 2011
The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitisSabrina Cipriani, Andrea Mencarelli, Maria Giovanna Chini, et al.
Organic & Biomolecular Chemistry|June 27, 2012
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonistValentina Sepe, Raffaella Ummarino, Maria Valeria D'Auria, et al.
Steroids|February 11, 2015
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonistsBarbara Renga, Carmen Festa, Simona De Marino, et al.
Marine Drugs|July 4, 2013
Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonistsCarmen Festa, Claudio D'Amore, Barbara Renga, et al.
Steroids|November 27, 2015
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activityValentina Sepe, Barbara Renga, Carmen Festa, et al.
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