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Journal of Medicinal Chemistry|September 24, 2014
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligandsCarmen Festa, Barbara Renga, Claudio D'Amore, et al.Scientific Reports|January 8, 2016
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonistsValentina Sepe, Carmen Festa, Barbara Renga, et al.Scientific Reports|July 7, 2016
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligandsClaudia Finamore, Carmen Festa, Barbara Renga, et al.Steroids|January 31, 2012
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunitySimona De Marino, Raffaella Ummarino, Maria Valeria D'Auria, et al.Plos One|February 1, 2012
Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasisBarbara Renga, Andrea Mencarelli, Claudio D'Amore, et al.Gastroenterology|October 19, 2005
Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugsStefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, et al.European Journal of Medicinal Chemistry|January 7, 2014
Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine spongesValentina Sepe, Claudio D'Amore, Raffella Ummarino, et al.Plos One|April 17, 2014
The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2Barbara Renga, Daniela Francisci, Elisabetta Schiaroli, et al.Journal of Medicinal Chemistry|August 28, 2014
Modification on ursodeoxycholic acid (UDCA) scaffold. discovery of bile acid derivatives as selective agonists of cell-surface G-protein coupled bile acid receptor 1 (GP-BAR1)Valentina Sepe, Barbara Renga, Carmen Festa, et al.Journal of Medicinal Chemistry|September 1, 2012
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γCarmen Festa, Gianluigi Lauro, Simona De Marino, et al.Pageof 10