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The Journal of Pharmacology and Experimental Therapeutics|August 21, 2010
The antiemetic 5-HT3 receptor antagonist Palonosetron inhibits substance P-mediated responses in vitro and in vivoCamilo Rojas, Ying Li, Jie Zhang, et al.ACS Chemical Neuroscience|September 3, 2021
High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan DiseaseOndřej Nešuta, Ajit G Thomas, Jesse Alt, et al.Molecular Psychiatry|June 22, 2022
Inhibition of glutamate-carboxypeptidase-II in dorsolateral prefrontal cortex: potential therapeutic target for neuroinflammatory cognitive disordersShengtao Yang, Dibyadeep Datta, Elizabeth Woo, et al.Bioconjugate Chemistry|November 20, 2012
Synthesis and biological evaluation of low molecular weight fluorescent imaging agents for the prostate-specific membrane antigenYing Chen, Mrudula Pullambhatla, Sangeeta R Banerjee, et al.Nature Reviews. Drug Discovery|September 22, 2015
Tackling reproducibility in academic preclinical drug discoveryStephen V Frye, Michelle R Arkin, Cheryl H Arrowsmith, et al.European Journal of Medicinal Chemistry|September 29, 2018
Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acidsYusuke Kato, Niyada Hin, Nobuo Maita, et al.Journal of Psychopharmacology (Oxford, England)|June 12, 2016
Oral administration of D-alanine in monkeys robustly increases plasma and cerebrospinal fluid levels but experimental D-amino acid oxidase inhibitors had minimal effectCamilo Rojas, Jesse Alt, Nancy A Ator, et al.Molecular Pharmaceutics|September 11, 2019
Enhanced Oral Bioavailability of 2-(Phosphonomethyl)-pentanedioic Acid (2-PMPA) from its (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (ODOL)-Based ProdrugsRanjeet P Dash, Tomáš Tichý, Vijayabhaskar Veeravalli, et al.Journal of Neurochemistry|September 30, 2005
Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injuryDean J Bacich, Krystyna M Wozniak, X-C May Lu, et al.Journal of Medicinal Chemistry|March 2, 2016
Discovery of Orally Available Prodrugs of the Glutamate Carboxypeptidase II (GCPII) Inhibitor 2-Phosphonomethylpentanedioic Acid (2-PMPA)Pavel Majer, Andrej Jančařík, Marcela Krečmerová, et al.Pageof 26