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Proceedings of the National Academy of Sciences of the United States of America|July 24, 2003
Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis modelsGhanashyam D Ghadge, Barbara S Slusher, Amos Bodner, et al.AIDS (London, England)|April 5, 2019
Intranasal insulin therapy reverses hippocampal dendritic injury and cognitive impairment in a model of HIV-associated neurocognitive disorders in EcoHIV-infected miceBoe-Hyun Kim, Jennifer Kelschenbach, Alejandra Borjabad, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|July 14, 2019
Unbiased Metabolic Profiling Predicts Sensitivity of High MYC-Expressing Atypical Teratoid/Rhabdoid Tumors to Glutamine Inhibition with 6-Diazo-5-Oxo-L-NorleucineSabrina Z Wang, Brad Poore, Jesse Alt, et al.Journal of Medicinal Chemistry|November 16, 2012
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitorsKrupa Shukla, Dana V Ferraris, Ajit G Thomas, et al.European Journal of Medicinal Chemistry|August 3, 2023
Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffoldKaterina Novotna, Ajit G Thomas, Ondrej Stepanek, et al.Journal of Medicinal Chemistry|November 10, 2023
Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor DeliveryKateřina Novotná, Lukáš Tenora, Eva Prchalová, et al.Cells|March 27, 2026
Microglial-Targeted GCPII Inhibition Reverses Neurocognitive Impairment and Synaptic Loss After EcoHIV InfectionYuxin Zheng, Meixiang Huang, R Michael Maragakis, et al.Journal of Medicinal Chemistry|October 30, 2019
Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic StabilityRachel D Slack, Therese C Ku, Jianjing Cao, et al.Current Drug Metabolism|September 7, 2021
Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target EngagementJesse Alt, Sadakatali S Gori, Kathryn M Lemberg, et al.Rapid Communications in Mass Spectrometry : RCM|June 12, 2024
Development of a high-throughput dual-stream liquid chromatography-tandem mass spectrometry method to screen for inhibitors of glutamate carboxypeptidase IINate Hoxie, Yixuan Qiu, Stephen C Kales, et al.Pageof 26