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Cell Death & Disease|April 28, 2022
Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumorsAshlyn Parkhurst, Sabrina Z Wang, Tyler R Findlay, et al.
Molecular Pharmaceutics|August 2, 2017
Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester ProdrugsMichael Nedelcovych, Ranjeet P Dash, Lukáš Tenora, et al.
European Journal of Nuclear Medicine and Molecular Imaging|January 1, 2025
JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imagingMichael T Nedelcovych, Ranjeet P Dash, Ying Wu, et al.
Proteomics|June 25, 2019
Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic CancerSunag Udupa, Stephanie Nguyen, Giang Hoang, et al.
Frontiers in Pharmacology|October 31, 2025
Mass spectrometry-guided discovery of novel GCPII inhibitor scaffoldsRobyn Wiseman, Ajit G Thomas, John Janiszewski, et al.
Alzheimer'S & Dementia (New York, N. Y.)|November 2, 2023
Chronic GCPII (glutamate-carboxypeptidase-II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaquesShveta Bathla, Dibyadeep Datta, Feng Liang, et al.
Research Square|July 28, 2023
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's diseaseCarolyn Tallon, Benjamin J Bell, Medhinee M Malvankar, et al.
Journal of Medicinal Chemistry|September 10, 2019
Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) AgonistsEva Prchalová, Niyada Hin, Ajit G Thomas, et al.
Journal of Neuroimmune Pharmacology : the Official Journal of the Society on Neuroimmune Pharmacology|June 19, 2019
Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive DisordersMichael T Nedelcovych, Boe-Hyun Kim, Xiaolei Zhu, et al.
Translational Neurodegeneration|December 4, 2023
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse modelCarolyn Tallon, Benjamin J Bell, Medhinee M Malvankar, et al.
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