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Nature Chemical Biology|March 21, 2018
An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channelMichaela Lichtenegger, Oleksandra Tiapko, Barbora Svobodova, et al.
Biochemical Pharmacology|February 11, 2021
7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivoMartina Kaniakova, Jan Korabecny, Kristina Holubova, et al.
International Journal of Molecular Sciences|June 10, 2023
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's DiseaseBarbora Svobodova, Lenka Pulkrabkova, Dawid Panek, et al.
European Journal of Medicinal Chemistry|January 13, 2024
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibitionAnna Misiachna, Barbora Svobodova, Jakub Netolicky, et al.
European Journal of Medicinal Chemistry|April 27, 2025
Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatmentBarbora Svobodova, Zuzana Moravcova, Anna Misiachna, et al.
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