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Orphanet Journal of Rare Diseases|June 19, 2012
A generalizable pre-clinical research approach for orphan disease therapyChandree L Beaulieu, Mark E Samuels, Sean Ekins, et al.
Pharmacoeconomics|June 27, 2019
Transparency in Decision Modelling: What, Why, Who and How?Christopher James Sampson, Renée Arnold, Stirling Bryan, et al.
Journal of Medicinal Chemistry|May 2, 2023
N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase InhibitorThomas Lane, Vadim Makarov, Julie A E Nelson, et al.
Aquatic Toxicology (Amsterdam, Netherlands)|May 1, 2010
Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitroDeanna L Howarth, Lee R Hagey, Sheran H W Law, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 3, 2009
The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulationYvonne S Lin, Kazuto Yasuda, Mahfoud Assem, et al.
Molecular Pharmacology|June 20, 2007
Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sitesSean Ekins, Cheng Chang, Sridhar Mani, et al.
Molecular Pharmacology|December 2, 2020
Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian ModelingSiennah R Miller, Xiaohong Zhang, Raymond K Hau, et al.
ACS Infectious Diseases|April 30, 2025
Cryo-EM Structure of HIV-1 Reverse Transcriptase with N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside InhibitorMegan A Young, Thomas R Lane, Renuka Raman, et al.
Molecular Pharmaceutics|December 15, 2020
Enzyme Replacement Therapy for Mucopolysaccharidosis IIID using Recombinant Human α-N-Acetylglucosamine-6-Sulfatase in Neonatal MiceFeng Wang, Derek R Moen, Chelsee Sauni, et al.
Plos One|October 31, 2015
Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug DiscoverySean Ekins, Peter B Madrid, Malabika Sarker, et al.
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