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The Journal of Clinical Investigation|May 12, 2010
COMMD1 disrupts HIF-1alpha/beta dimerization and inhibits human tumor cell invasionBart van de Sluis, Xicheng Mao, Yali Zhai, et al.
Cell Reports|September 22, 2021
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolismLeen Catrysse, Bastiaan Maes, Parul Mehrotra, et al.
Biochimica Et Biophysica Acta. Molecular Cell Research|July 21, 2017
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammationTabea Riedlinger, Marleen B Dommerholt, Tobias Wijshake, et al.
Hepatology (Baltimore, Md.)|December 15, 2015
Identification of p38 MAPK and JNK as new targets for correction of Wilson disease-causing ATP7B mutantsGiancarlo Chesi, Ramanath N Hegde, Simona Iacobacci, et al.
Nature Communications|June 25, 2014
Chronic inflammation induces telomere dysfunction and accelerates ageing in miceDiana Jurk, Caroline Wilson, João F Passos, et al.
Molecular Metabolism|October 9, 2021
The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesisAndries Heida, Nanda Gruben, Leen Catrysse, et al.
Hepatology (Baltimore, Md.)|June 22, 2021
Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene EditingMartijn G S Rutten, Terry G J Derks, Nicolette C A Huijkman, et al.
Journal of Lipid Research|June 25, 2026
Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulationJinxiao Li, Hilde D de Vries, Kirill Ustyantsev, et al.
Molecular Metabolism|June 10, 2026
Hepatocyte-specific Cas9-mediated editing of G6pc and Slc37a4 elicits comparable biochemical and regulatory responses between glycogen storage disease (GSD) type Ia and Ib miceKishore A Krishnamurthy, Ruiqi Xiao, Martijn G S Rutten, et al.
Circulation Research|March 17, 2018
The COMMD Family Regulates Plasma LDL Levels and Attenuates Atherosclerosis Through Stabilizing the CCC Complex in Endosomal LDLR TraffickingAlina Fedoseienko, Melinde Wijers, Justina C Wolters, et al.
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