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Research and Practice in Thrombosis and Haemostasis|March 25, 2025
Identification and characterization of factor XI autoantibodies in 2 patients with systemic lupus erythematosus: insights into mechanisms of acquired factor XI deficiencyPriyanka Srivastava, Amy Zhou, Christine Fuja, et al.
The New England Journal of Medicine|November 15, 2021
Milvexian for the Prevention of Venous ThromboembolismJeffrey I Weitz, John Strony, Walter Ageno, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 5, 2021
Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XIKatherine J Kearney, Juliet Butler, Olga M Posada, et al.
Frontiers in Pharmacology|January 5, 2024
Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activationAllen C Clermont, Nivetha Murugesan, Hannah J Edwards, et al.
Blood|November 22, 2023
A mechanism for hereditary angioedema caused by a methionine-379-to-lysine substitution in kininogensS Kent Dickeson, Sunil Kumar, Mao-Fu Sun, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|August 8, 2009
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2)Tara C White-Adams, Michelle A Berny, Erik I Tucker, et al.
Plos One|April 6, 2016
Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in MiceCharles E Bane, Ivan Ivanov, Anton Matafonov, et al.
Research and Practice in Thrombosis and Haemostasis|June 17, 2020
The contact activation system as a potential therapeutic target in patients with COVID-19Joseph J Shatzel, Emma P DeLoughery, Christina U Lorentz, et al.
Research and Practice in Thrombosis and Haemostasis|February 29, 2020
Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primatesMichael Wallisch, Christina U Lorentz, Hari H S Lakshmanan, et al.
Metabolic Brain Disease|June 21, 2023
Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in miceTia C L Kohs, Meghan E Fallon, Ethan C Oseas, et al.
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