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Protein Science : a Publication of the Protein Society|August 30, 2008
Structural evidence for substrate-induced synergism and half-sites reactivity in biotin carboxylaseIgor Mochalkin, J Richard Miller, Artem Evdokimov, et al.Bioorganic & Medicinal Chemistry Letters|September 5, 2021
Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitorsYufang Xiao, Bayard R Huck, Ruoxi Lan, et al.Protein Science : a Publication of the Protein Society|November 22, 2007
Characterization of substrate binding and catalysis in the potential antibacterial target N-acetylglucosamine-1-phosphate uridyltransferase (GlmU)Igor Mochalkin, Sandra Lightle, Yaqi Zhu, et al.International Journal for Parasitology. Drugs and Drug Resistance|June 13, 2020
Identification of annotated bioactive molecules that impair motility of the blood fluke Schistosoma mansoniThomas B Duguet, Anastasia Glebov, Asimah Hussain, et al.Bioorganic & Medicinal Chemistry Letters|March 21, 2006
The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonistsBayard R Huck, Luis Llamas, Michael J Robarge, et al.Bioorganic & Medicinal Chemistry Letters|June 6, 2006
The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonistBayard R Huck, Luis Llamas, Michael J Robarge, et al.ACS Chemical Biology|May 6, 2009
Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approachesIgor Mochalkin, J Richard Miller, Lakshmi Narasimhan, et al.Journal of Medicinal Chemistry|August 2, 2019
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological DiseasesRichard D Caldwell, Hui Qiu, Ben C Askew, et al.Bioorganic & Medicinal Chemistry Letters|October 7, 2018
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of BtkRichard Caldwell, Lesley Liu-Bujalski, Hui Qiu, et al.Bioorganic & Medicinal Chemistry Letters|August 21, 2018
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hitHui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, et al.Pageof 4