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Chemico-Biological Interactions|March 22, 2024
Thiazolyl-isatin derivatives: Synthesis, in silico studies, in vitro biological profile against breast cancer cells, mRNA expression, P-gp modulation, and interactions of Akt2 and VIM proteinsLuiz Alberto Barros Freitas, Carolina Sousa, Beatriz Silva Lima, et al.Hepatology (Baltimore, Md.)|October 25, 2016
Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryChristopher Goldring, Daniel J Antoine, Frank Bonner, et al.Regulatory Toxicology and Pharmacology : RTP|August 1, 2014
Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trialsFiona Sewell, Kathryn Chapman, Paul Baldrick, et al.Nature Biotechnology|May 12, 2010
Towards consensus practices to qualify safety biomarkers for use in early drug developmentFrank D Sistare, Frank Dieterle, Sean Troth, et al.Nature Reviews. Drug Discovery|March 2, 2010
Challenges with advanced therapy medicinal products and how to meet them, , Christian K Schneider, et al.Nature Biotechnology|May 12, 2010
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing ConsortiumFrank Dieterle, Frank Sistare, Federico Goodsaid, et al.Pageof 5