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Molecular Cell|October 22, 2019
Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS MutationsAmirhossein Ghanbari Niaki, Jaya Sarkar, Xinyi Cai, et al.
Nature Metabolism|July 8, 2026
Hypoxia rescues complex 1-associated disease caused by proteostatic defectsAnkur Garg, Brandon R Desousa, Raju Roy, et al.
Biorxiv : the Preprint Server for Biology|July 14, 2025
Scouring the human Hsp70 network uncovers diverse chaperone safeguards buffering TDP-43 toxicityEdward M Barbieri, Miriam Linsenmeier, Katherine R Whiteman, et al.
Nature Genetics|October 30, 2012
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease modelsMaria Armakola, Matthew J Higgins, Matthew D Figley, et al.
Molecular Biology of the Cell|December 12, 2019
The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrateRamon D Jones, Charisma Enam, Rebeca Ibarra, et al.
Cell Reports|December 28, 2020
Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological InteractionsSaskia Hutten, Sinem Usluer, Benjamin Bourgeois, et al.
Cell Reports|December 2, 2020
TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's DiseaseGuixin Zhu, Dilshan S Harischandra, Shivani Ghaisas, et al.
Biorxiv : the Preprint Server for Biology|June 19, 2024
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUSSonia Vazquez-Sanchez, Britt Tilkin, Fatima Gasset-Rosa, et al.
Molecular Neurodegeneration|June 11, 2024
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUSSonia Vazquez-Sanchez, Britt Tilkin, Fatima Gasset-Rosa, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 29, 2007
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasisAaron D Gitler, Brooke J Bevis, James Shorter, et al.
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