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Cell Chemical Biology|February 9, 2016
Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding ProteinsBen E Clifton, Colin J Jackson
Biochemistry|March 4, 2022
Efficient Exploration of Sequence Space by Sequence-Guided Protein Engineering and DesignBen E Clifton, Dan Kozome, Paola Laurino
Nucleic Acids Research|November 11, 2021
Evolutionary repair reveals an unexpected role of the tRNA modification m1G37 in aminoacylationBen E Clifton, Muhammad A Fariz, Gen-Ichiro Uechi, et al.
Protein Science : a Publication of the Protein Society|November 16, 2022
The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activityNicholas J East, Ben E Clifton, Colin J Jackson, et al.
Nucleic Acids Research|October 17, 2024
SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiencyYoshiki Ochiai, Ben E Clifton, Madeleine Le Coz, et al.
Nature|September 11, 2024
The ultra-high affinity transport proteins of ubiquitous marine bacteriaBen E Clifton, Uria Alcolombri, Gen-Ichiro Uechi, et al.
Nature Chemical Biology|April 25, 2018
Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding proteinBen E Clifton, Joe A Kaczmarski, Paul D Carr, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 16, 2017
Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET SensorsBen E Clifton, Jason H Whitfield, Inmaculada Sanchez-Romero, et al.
Protein Science : a Publication of the Protein Society|June 11, 2015
Construction of a robust and sensitive arginine biosensor through ancestral protein reconstructionJason H Whitfield, William H Zhang, Michel K Herde, et al.
Nature Communications|November 24, 2020
Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzymeJoe A Kaczmarski, Mithun C Mahawaththa, Akiva Feintuch, et al.
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