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Molecular Metabolism|November 30, 2025
Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesityManu V Chakravarthy, Ruben Rodriguez, Anne Hergarden, et al.Bioorganic & Medicinal Chemistry|May 30, 2019
Optimization of novel reversible Bruton's tyrosine kinase inhibitors identified using Tethering-fragment-based screensBrian T Hopkins, Eris Bame, Noah Bell, et al.Applied Biosafety : Journal of the American Biological Safety Association|June 21, 2023
The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Shigella sppStuart D Blacksell, Sandhya Dhawan, Marina Kusumoto, et al.Bioorganic & Medicinal Chemistry Letters|April 5, 2011
Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discoveryDaniel A Erlanson, Joseph W Arndt, Mark T Cancilla, et al.Bioorganic & Medicinal Chemistry|July 27, 2021
Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitorsBrian T Hopkins, Eris Bame, Noah Bell, et al.ACS Medicinal Chemistry Letters|September 19, 2019
Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12CYoungsook Shin, Joon Won Jeong, Ryan P Wurz, et al.Pageof 5