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Plos Genetics|January 25, 2018
Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functionsZuchra Zakirova, Tomas Fanutza, Justine Bonet, et al.Nature Communications|August 25, 2019
Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traitsWen Zhang, Georgios Voloudakis, Veera M Rajagopal, et al.Circulation. Genomic and Precision Medicine|May 7, 2019
Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral TherapyItziar Frades, Ben Readhead, Letizia Amadori, et al.Briefings in Bioinformatics|February 16, 2017
Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioningKhader Shameer, Benjamin S Glicksberg, Rachel Hodos, et al.Nature Neuroscience|August 1, 2017
Necroptosis activation in Alzheimer's diseaseAntonella Caccamo, Caterina Branca, Ignazio S Piras, et al.Molecular Psychiatry|October 5, 2018
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burdenJean-Vianney Haure-Mirande, Minghui Wang, Mickael Audrain, et al.Molecular Psychiatry|November 23, 2018
Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burdenJean-Vianney Haure-Mirande, Minghui Wang, Mickael Audrain, et al.Acta Neuropathologica|June 15, 2017
Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathologyJean-Vianney Haure-Mirande, Mickael Audrain, Tomas Fanutza, et al.Molecular Cancer Therapeutics|June 18, 2020
A Novel Approach to Safer Glucocorticoid Receptor-Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) InhibitionEkaterina A Lesovaya, Alena V Savinkova, Olga V Morozova, et al.The Lancet. Psychiatry|February 27, 2016
Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approachDouglas M Ruderfer, Alexander W Charney, Ben Readhead, et al.Pageof 5