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Biorxiv : the Preprint Server for Biology|February 26, 2024
Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activityJoshua Gerninghaus, Rezart Zhubi, Andreas Krämer, et al.
Journal of Medicinal Chemistry|July 13, 2026
Riding toward Selectivity: Optimization of Covalent 7-Azaindole-Based BMX Kinase InhibitorsXiaojun Julia Liang, Claudia Albertini, Thales Kronenberger, et al.
Frontiers in Cell and Developmental Biology|June 20, 2022
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing ProteinsMartin P Schwalm, Lena M Berger, Maximilian N Meuter, et al.
International Journal of Cancer|June 30, 2020
Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinomaXin Zhang, Tim Zegar, Tim Weiser, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Un-LOK-ing a New Approach for Conformational Selective Targeting of STK10 (LOK)Martina Dettenhöfer, Laura Nadine Tandara, Jennifer Alisa Amrhein, et al.
ACS Chemical Biology|April 14, 2025
Repurposing of the RIPK1-Selective Benzo[1,4]oxazepin-4-one Scaffold for the Development of a Type III LIMK1/2 InhibitorSebastian Mandel, Thomas Hanke, Sebastian Mathea, et al.
Journal of Medicinal Chemistry|October 20, 2021
Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric SitesFlorian Wittlinger, David E Heppner, Ciric To, et al.
Journal of Medicinal Chemistry|July 2, 2025
Covalent Targeting Leads to the Development of a LIMK1 Isoform-Selective InhibitorSebastian Mandel, Thomas Hanke, Niall Prendiville, et al.
Journal of Medicinal Chemistry|February 16, 2019
SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK)Christopher R M Asquith, Benedict-Tilman Berger, Jing Wan, et al.
Journal of Medicinal Chemistry|July 18, 2024
Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2Václav Němec, Marek Remeš, Petr Beňovský, et al.
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