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Proceedings of the National Academy of Sciences of the United States of America|June 6, 2002
Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formationDieter Edbauer, Edith Winkler, Christian Haass, et al.Acta Neuropathologica|August 15, 2014
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestrationStephanie May, Daniel Hornburg, Martin H Schludi, et al.The Journal of Biological Chemistry|March 25, 2004
Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the gamma-secretase complexStefan Prokop, Keiro Shirotani, Dieter Edbauer, et al.Journal of Neurochemistry|June 11, 2004
Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1Keiro Shirotani, Dieter Edbauer, Marcus Kostka, et al.The Journal of Biological Chemistry|August 3, 2004
Identification of distinct gamma-secretase complexes with different APH-1 variantsKeiro Shirotani, Dieter Edbauer, Stefan Prokop, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|May 3, 2013
Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signalingDaniel Fleck, Frauke van Bebber, Alessio Colombo, et al.The Journal of Biological Chemistry|January 26, 2002
Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)Dieter Edbauer, Michael Willem, Sven Lammich, et al.Current Biology : CB|October 16, 2007
Role of Septin cytoskeleton in spine morphogenesis and dendrite development in neuronsTomoko Tada, Alyson Simonetta, Matthew Batterton, et al.The Journal of Biological Chemistry|March 20, 2003
Gamma-secretase activity is associated with a conformational change of nicastrinKeiro Shirotani, Dieter Edbauer, Anja Capell, et al.Nature Cell Biology|April 8, 2003
Reconstitution of gamma-secretase activityDieter Edbauer, Edith Winkler, Joerg T Regula, et al.Pageof 11