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The EMBO Journal|November 19, 2004
The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activityChristoph Kaether, Anja Capell, Dieter Edbauer, et al.
The Journal of Biological Chemistry|November 7, 2003
Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domainAnja Capell, Christoph Kaether, Dieter Edbauer, et al.
The Journal of Cell Biology|July 31, 2002
Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membraneChristoph Kaether, Sven Lammich, Dieter Edbauer, et al.
The Journal of Biological Chemistry|August 29, 2002
PEN-2 is an integral component of the gamma-secretase complex required for coordinated expression of presenilin and nicastrinHarald Steiner, Edith Winkler, Dieter Edbauer, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|February 19, 2010
Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiationKelly A Foster, Nathan McLaughlin, Dieter Edbauer, et al.
Molecular Neurodegeneration|January 16, 2017
Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegenerationYu Ohki, Andrea Wenninger-Weinzierl, Alexander Hruscha, et al.
The EMBO Journal|July 9, 2014
MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's diseaseJulia Banzhaf-Strathmann, Eva Benito, Stephanie May, et al.
The EMBO Journal|September 14, 2016
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neuronsBenjamin M Schwenk, Hannelore Hartmann, Alperen Serdaroglu, et al.
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration|January 2, 2026
Homozygosity for the C allele at UNC13A rs12608932 seems to compromise cognition in ALS independently of the cognitive domainsAnnaliis Lehto, Andreas Zapf, Andreas Hermann, et al.
Acta Neuropathologica|January 22, 2014
Early dipeptide repeat pathology in a frontotemporal dementia kindred with C9ORF72 mutation and intellectual disabilityMalcolm Proudfoot, Nick J Gutowski, Dieter Edbauer, et al.
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