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Molecular Cell|March 4, 2008
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box moduleDavid Komander, Christopher J Lord, Hartmut Scheel, et al.
Molecular Biology of the Cell|September 5, 2008
An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingDavid Komander, Manishha Patel, Mélanie Laurin, et al.
EMBO Reports|March 15, 2011
Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21Yu Ye, Masato Akutsu, Francisca Reyes-Turcu, et al.
Nature Microbiology|May 9, 2017
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κBJessica Noad, Alexander von der Malsburg, Claudio Pathe, et al.
EMBO Reports|April 18, 2009
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chainsDavid Komander, Francisca Reyes-Turcu, Julien D F Licchesi, et al.
The EMBO Journal|November 15, 2017
An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1Christina Gladkova, Alexander F Schubert, Jane L Wagstaff, et al.
Molecular Cell|March 31, 2019
Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating ActivityMalte Gersch, Jane L Wagstaff, Angela V Toms, et al.
Organic Letters|November 28, 2017
Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin MonomerGerbrand J van der Heden van Noort, Raymond Kooij, Paul R Elliott, et al.
The Journal of Biological Chemistry|June 17, 2021
A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domainTaylor P Light, Maricel Gomez-Soler, Zichen Wang, et al.
The Biochemical Journal|August 2, 2003
Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibitionDavid Komander, Gursant S Kular, Jennifer Bain, et al.
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