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Bone|January 26, 2010
The resorptive apparatus of osteoclasts supports lysosomotropism and increases potency of basic versus non-basic inhibitors of cathepsin KKaren Fuller, Erik Lindstrom, Michael Edlund, et al.Journal of Medicinal Chemistry|February 5, 2010
Design and synthesis of potent and selective BACE-1 inhibitorsCatarina Björklund, Stefan Oscarson, Kurt Benkestock, et al.European Journal of Medicinal Chemistry|December 29, 2009
Synthesis of potent BACE-1 inhibitors incorporating a hydroxyethylene isostere as central coreFredrik Wångsell, Karin Gustafsson, Ingemar Kvarnström, et al.Journal of Medicinal Chemistry|December 30, 2003
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activityKarolina Ersmark, Isabella Feierberg, Sinisa Bjelic, et al.Bioorganic & Medicinal Chemistry|January 7, 2009
Solid-phase parallel synthesis and SAR of 4-amidofuran-3-one inhibitors of cathepsin S: effect of sulfonamides P3 substituents on potency and selectivitySusana Ayesa, Charlotta Lindquist, Tatiana Agback, et al.Bioorganic & Medicinal Chemistry|October 10, 2008
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residuesMarcus Bäck, Jonas Nyhlén, Ingemar Kvarnström, et al.Journal of Medicinal Chemistry|December 8, 2009
HIV-1 protease inhibitors with a transition-state mimic comprising a tertiary alcohol: improved antiviral activity in cellsA K Mahalingam, Linda Axelsson, Jenny K Ekegren, et al.European Journal of Biochemistry|November 25, 2004
Symmetric fluoro-substituted diol-based HIV protease inhibitors. Ortho-fluorinated and meta-fluorinated P1/P1'-benzyloxy side groups significantly improve the antiviral activity and preserve binding efficacyJimmy Lindberg, David Pyring, Seved Löwgren, et al.Journal of Medicinal Chemistry|September 16, 2005
Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulationsKarolina Ersmark, Martin Nervall, Elizabeth Hamelink, et al.Journal of Medicinal Chemistry|June 11, 2004
Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifsPer-Ola Johansson, Yantao Chen, Anna Karin Belfrage, et al.Pageof 7