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Beth Williamson

Showing results (21-30 of 29) with videos related to

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Archives of Toxicology|January 1, 2022
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessmentGregory Hamm, Gareth Maglennon, Beth Williamson, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 11, 2026
In vitro reversible enzyme inhibition assays to predict drug-drug interactions: Current state and industry perspective from the IQ Consortium Enzyme Inhibition Working GroupCarlo Sensenhauser, Sarah M Glass, Upendra P Dahal, et al.
Bioorganic & Medicinal Chemistry Letters|March 8, 2021
Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferaseDaniel H O' Donovan, Clare Gregson, Martin J Packer, et al.
Journal of Medicinal Chemistry|December 19, 2019
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a</i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H</i>-pyran-4-yl)-7,9-dihydro-8<i>H</i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) InhibitorFrederick W Goldberg, M Raymond V Finlay, Attilla K T Ting, et al.
ACS Medicinal Chemistry Letters|August 18, 2022
Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8<i>H</i>-purin-8-one Inhibitors of DNA-PKFrederick W Goldberg, Attilla K T Ting, David Beattie, et al.
Journal of Medicinal Chemistry|November 22, 2021
Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 MethyltransferaseSharan K Bagal, Clare Gregson, Daniel H O' Donovan, et al.
Journal of Medicinal Chemistry|March 11, 2024
Development of a Series of Pyrrolopyridone MAT2A InhibitorsStephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, et al.
Communications Biology|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTACThomas G Hayhow, Beth Williamson, Mandy Lawson, et al.
Journal of Medicinal Chemistry|September 3, 2021
Optimization of an Imidazo[1,2-<i>a</i>]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with <i>In Vivo</i> EfficacyWilliam McCoull, Scott Boyd, Martin R Brown, et al.
Pageof 3

Showing results (21-30 of 29) with videos related to

Sort By:
Pageof 3
You have reached the last page of results.This site can display upto 29 results.
Archives of Toxicology|January 1, 2022
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessmentGregory Hamm, Gareth Maglennon, Beth Williamson, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 11, 2026
In vitro reversible enzyme inhibition assays to predict drug-drug interactions: Current state and industry perspective from the IQ Consortium Enzyme Inhibition Working GroupCarlo Sensenhauser, Sarah M Glass, Upendra P Dahal, et al.
Bioorganic & Medicinal Chemistry Letters|March 8, 2021
Free energy perturbation in the design of EED ligands as inhibitors of polycomb repressive complex 2 (PRC2) methyltransferaseDaniel H O' Donovan, Clare Gregson, Martin J Packer, et al.
Journal of Medicinal Chemistry|December 19, 2019
The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a</i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H</i>-pyran-4-yl)-7,9-dihydro-8<i>H</i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) InhibitorFrederick W Goldberg, M Raymond V Finlay, Attilla K T Ting, et al.
ACS Medicinal Chemistry Letters|August 18, 2022
Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8<i>H</i>-purin-8-one Inhibitors of DNA-PKFrederick W Goldberg, Attilla K T Ting, David Beattie, et al.
Journal of Medicinal Chemistry|November 22, 2021
Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 MethyltransferaseSharan K Bagal, Clare Gregson, Daniel H O' Donovan, et al.
Journal of Medicinal Chemistry|March 11, 2024
Development of a Series of Pyrrolopyridone MAT2A InhibitorsStephen J Atkinson, Sharan K Bagal, Argyrides Argyrou, et al.
Communications Biology|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTACThomas G Hayhow, Beth Williamson, Mandy Lawson, et al.
Journal of Medicinal Chemistry|September 3, 2021
Optimization of an Imidazo[1,2-<i>a</i>]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with <i>In Vivo</i> EfficacyWilliam McCoull, Scott Boyd, Martin R Brown, et al.
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