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Current Opinion in Structural Biology|July 30, 2016
The growing structural and functional complexity of the LSD1/KDM1A histone demethylaseChiara Marabelli, Biagina Marrocco, Andrea MatteviJournal of Medicinal Chemistry|December 19, 2015
Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase InhibitorsDamodara N Reddy, Flavio Ballante, Timothy Chuang, et al.ACS Chemical Biology|September 1, 2015
Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer AgentsValentina Piano, Daniel I Benjamin, Sergio Valente, et al.Science Advances|September 15, 2016
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural featuresValentina Speranzini, Dante Rotili, Giuseppe Ciossani, et al.Cell Reports|April 11, 2019
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric ComplexChiara Marabelli, Biagina Marrocco, Simona Pilotto, et al.Autoimmunity|January 21, 2016
Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine modelRosa Di Liddo, Sergio Valente, Samanta Taurone, et al.Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences|April 25, 2018
Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cellsPaolo Mellini, Biagina Marrocco, Diana Borovika, et al.Journal of Medicinal Chemistry|June 17, 2014
Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymesDante Rotili, Domenico Tarantino, Maxim B Nawrozkij, et al.ACS Medicinal Chemistry Letters|February 21, 2015
Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell StudiesSergio Valente, Veronica Rodriguez, Ciro Mercurio, et al.Journal of Medicinal Chemistry|December 26, 2015
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor AgentPaola Vianello, Oronza A Botrugno, Anna Cappa, et al.Pageof 2