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Nature Protocols|January 8, 2016
Molecular mechanisms of protein aggregation from global fitting of kinetic modelsGeorg Meisl, Julius B Kirkegaard, Paolo Arosio, et al.Translational Neurodegeneration|October 17, 2025
Disease-disease interactions: molecular links of neurodegenerative diseases with cancer, viral infections, and type 2 diabetesYuxi Lin, Je Min Yoo, Yan Li, et al.Proceedings of the National Academy of Sciences of the United States of America|September 28, 2018
SAR by kinetics for drug discovery in protein misfolding diseasesSean Chia, Johnny Habchi, Thomas C T Michaels, et al.ACS Chemical Neuroscience|August 12, 2021
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and TrodusquemineSilvia Errico, Hassan Ramshini, Claudia Capitini, et al.Molecular Systems Biology|November 5, 2025
Identification of potent high-affinity secondary nucleation inhibitors of Aβ42 aggregation from an ultra-large chemical library using deep dockingMichaela Brezinova, Z Faidon Brotzakis, Robert I Horne, et al.International Journal of Molecular Sciences|November 20, 2020
Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein OligomersRyan P Kreiser, Aidan K Wright, Natalie R Block, et al.Proceedings of the National Academy of Sciences of the United States of America|May 15, 2023
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chainsAlyssa Miller, Jiapeng Wei, Sarah Meehan, et al.Journal of Chemical Information and Modeling|January 23, 2024
Using Generative Modeling to Endow with Potency Initially Inert Compounds with Good Bioavailability and Low ToxicityRobert I Horne, Jared Wilson-Godber, Alicia González Díaz, et al.International Journal of Clinical and Experimental Pathology|October 12, 2020
HMGB1-induced autophagy promotes extracellular matrix degradation leading to intervertebral disc degenerationBiao Fu, Xia Lu, Er-Yang Zhao, et al.Science Advances|November 11, 2022
Fragment-based computational design of antibodies targeting structured epitopesMauricio Aguilar Rangel, Alice Bedwell, Elisa Costanzi, et al.Pageof 62