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Blood|February 11, 2012
F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferationBill B Chen, Jennifer R Glasser, Tiffany A Coon, et al.
Redox Biology|March 16, 2020
A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axisYanwen Chen, John W Evankovich, Travis B Lear, et al.
Journal of Cellular Biochemistry|October 14, 2020
SCF FBXW17 E3 ubiquitin ligase regulates FBXL19 stability and cell migrationSu Dong, Jianxin Wei, Rachel K Bowser, et al.
Science Translational Medicine|October 30, 2015
Mortality factor 4 like 1 protein mediates epithelial cell death in a mouse model of pneumoniaChunbin Zou, Jin Li, Sheng Xiong, et al.
Nature Communications|May 12, 2017
Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activityJoseph S Bednash, Nathaniel Weathington, James Londino, et al.
Frontiers in Pharmacology|February 11, 2022
A Repurposed Drug Screen for Compounds Regulating Aquaporin 5 Stability in Lung Epithelial CellsJohn Villandre, Virginia White, Travis B Lear, et al.
Journal of Immunology (Baltimore, Md. : 1950)|October 15, 2013
Targeting F box protein Fbxo3 to control cytokine-driven inflammationRama K Mallampalli, Tiffany A Coon, Jennifer R Glasser, et al.
Elife|November 3, 2016
RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunityAlison C McKelvey, Travis B Lear, Sarah R Dunn, et al.
The Journal of Biological Chemistry|June 4, 2015
Lipopolysaccharide Primes the NALP3 Inflammasome by Inhibiting Its Ubiquitination and Degradation Mediated by the SCFFBXL2 E3 LigaseSeungHye Han, Travis B Lear, Jacob A Jerome, et al.
American Journal of Respiratory Cell and Molecular Biology|August 7, 2019
Toll-like Receptor 8 Stability Is Regulated by Ring Finger 216 in Response to Circulating MicroRNAsJohn Evankovich, Travis Lear, Courtney Baldwin, et al.
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