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Cell Reports|March 18, 2014
Caspase-11 controls interleukin-1β release through degradation of TRPC1Bénédicte F Py, Mingzhi Jin, Bimal N Desai, et al.Developmental Cell|June 16, 2012
Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosisBimal N Desai, Grigory Krapivinsky, Betsy Navarro, et al.Science Advances|November 23, 2022
Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolismScott Yeudall, Clint M Upchurch, Philip V Seegren, et al.Elife|December 22, 2020
Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1Sean R Cuddy, Austin R Schinlever, Sara Dochnal, et al.Nature Communications|June 10, 2022
Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activityMichael S Schappe, Marta E Stremska, Gregory W Busey, et al.The Journal of General Physiology|November 9, 2023
Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effectsGregory W Busey, Mohan C Manjegowda, Tao Huang, et al.Biorxiv : the Preprint Server for Biology|September 4, 2023
Novel TRPM7 inhibitors with potent anti-inflammatory effects in vivoGregory W Busey, Mohan C Manjegowda, Tao Huang, et al.Nature Aging|June 5, 2023
Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammagingPhilip V Seegren, Logan R Harper, Taylor K Downs, et al.Science Signaling|December 9, 2020
Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signalingSuresh K Mendu, Marta E Stremska, Michael S Schappe, et al.Cell Reports|November 25, 2020
Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome KillingPhilip V Seegren, Taylor K Downs, Marta E Stremska, et al.Pageof 3