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Elife|November 27, 2019
The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channelsAlessandro Porro, Andrea Saponaro, Federica Gasparri, et al.Proceedings of the National Academy of Sciences of the United States of America|September 9, 2014
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel functionAndrea Saponaro, Sofia R Pauleta, Francesca Cantini, et al.Nature Communications|January 29, 2024
A high affinity switch for cAMP in the HCN pacemaker channelsAlessandro Porro, Andrea Saponaro, Roberta Castelli, et al.Cell|November 20, 2004
A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neuronsMatthew F Nolan, Gaël Malleret, Josh T Dudman, et al.Cell|December 4, 2003
The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cellsMatthew F Nolan, Gaël Malleret, Ka Hung Lee, et al.Elife|June 21, 2018
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channelsAndrea Saponaro, Francesca Cantini, Alessandro Porro, et al.Elife|August 16, 2022
Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of <i>HCN1</i> epileptic encephalopathyAndrea Merseburg, Jacquelin Kasemir, Eric W Buss, et al.Brain : a Journal of Neurology|April 6, 2021
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathyLauren E Bleakley, Chaseley E McKenzie, Ming S Soh, et al.Molecular Cell|June 24, 2021
Gating movements and ion permeation in HCN4 pacemaker channelsAndrea Saponaro, Daniel Bauer, M Hunter Giese, et al.Biorxiv : the Preprint Server for Biology|March 27, 2026
Comprehensive classification of HCN1 variants linked to neurodevelopmental disorders with and without epilepsyRoberta Castelli, Carla Marini, Alessandro Porro, et al.Pageof 4