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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|August 13, 2002
Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cellsMichael H Wu, Bingfang Yan, Rod Humerickhouse, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 18, 2002
Mouse liver and kidney carboxylesterase (M-LK) rapidly hydrolyzes antitumor prodrug irinotecan and the N-terminal three quarter sequence determines substrate selectivityMingxing Xie, Dongfang Yang, Micheal Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 16, 2004
Simultaneous substitution of phenylalanine-305 and aspartate-318 of rat pregnane X receptor with the corresponding human residues abolishes the ability to transactivate the CYP3A23 promoterXiulong Song, Yuxin Li, Jirong Liu, et al.
BMC Molecular Biology|March 1, 2006
Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expressionXiaoming Gong, Shu-Whei Tsai, Bingfang Yan, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2002
Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expressionMingxing Xie, Dongfang Yang, Lan Liu, et al.
Molecular Pharmacology|June 1, 2007
Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2Jian Yang, Deshi Shi, Dongfang Yang, et al.
Small (Weinheim an Der Bergstrasse, Germany)|July 26, 2012
Hollow copper sulfide nanoparticle-mediated transdermal drug deliverySamy Ramadan, Liangran Guo, Yajuan Li, et al.
Current Drug Metabolism|December 14, 2022
Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug IrinotecanWilliam Eades, William Liu, Yue Shen, et al.
British Journal of Pharmacology|June 9, 2011
Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitorDongfang Yang, Jian Yang, Deshi Shi, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 17, 2009
Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinedionesRajani Kaimal, Xiulong Song, Bingfang Yan, et al.
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