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The Journal of Pharmacology and Experimental Therapeutics|December 1, 2006
The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonismRuitang Deng, Dongfang Yang, Amy Radke, et al.The Biochemical Journal|September 4, 2007
The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alphaFu-Jun Liu, Xiulong Song, Dongfang Yang, et al.Toxicology and Applied Pharmacology|March 3, 2009
Pyrethroid insecticides: isoform-dependent hydrolysis, induction of cytochrome P450 3A4 and evidence on the involvement of the pregnane X receptorDongfang Yang, Xiliang Wang, Yi-Tzai Chen, et al.The Journal of Infectious Diseases|March 16, 2011
Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivirDeshi Shi, Dongfang Yang, Eric P Prinssen, et al.British Journal of Pharmacology|February 5, 2013
Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrugDa Xiao, Dongfang Yang, Liangran Guo, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 8, 2004
The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genesXiulong Song, Mingxing Xie, He Zhang, et al.The Biochemical Journal|June 15, 2004
DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1Yuxin Li, Xiulong Song, Yuzhong Ma, et al.Biochemical Pharmacology|December 12, 2012
Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugsDa Xiao, Deshi Shi, Dongfang Yang, et al.Hepatology (Baltimore, Md.)|April 15, 2014
Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancyXiulong Song, Alexander Vasilenko, Yuan Chen, et al.Journal of Lipid Research|September 5, 2013
Mechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptorXiulong Song, Yuan Chen, Leila Valanejad, et al.Pageof 10