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Nature Communications|April 21, 2018
The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasomeFiachra Humphries, Ronan Bergin, Ruaidhri Jackson, et al.
The Journal of Experimental Medicine|August 31, 2019
Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitisSheng Li, Yuqing Wu, Dongxue Yang, et al.
The Journal of Experimental Medicine|March 12, 2021
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitisChunmei Ma, Sheng Li, Yingchao Hu, et al.
EMBO Molecular Medicine|January 4, 2024
Gasdermin D in macrophages drives orchitis by regulating inflammation and antigen presentation processesChunmei Ma, Jiajia Huang, Yuying Jiang, et al.
Cell Chemical Biology|November 1, 2024
Identification of two repurposed drugs targeting GSDMD oligomerization interface I to block pyroptosisYingchao Hu, Honghui Li, Xiangyu Zhang, et al.
Acta Pharmaceutica Sinica. B|July 10, 2023
GSDMD in peripheral myeloid cells regulates microglial immune training and neuroinflammation in Parkinson's diseaseBingwei Wang, Yan Ma, Sheng Li, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|July 6, 2023
ECSIT Is a Critical Factor for Controlling Intestinal Homeostasis and Tumorigenesis through Regulating the Translation of YAP ProteinYuying Jiang, Chunmei Ma, Yingchao Hu, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 2, 2022
The Gasdermin D N-terminal fragment acts as a negative feedback system to inhibit inflammasome-mediated activation of Caspase-1/11Yingchao Hu, Yuying Jiang, Sheng Li, et al.
Journal of Proteome Research|April 11, 2024
Proteomics Platform Reveals Broad-Spectrum Nanobodies for SARS-CoV-2 Variant NeutralizationRan Zhang, Lan Huang, Xiaohan Zhang, et al.
Nature Immunology|October 9, 2012
Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferonsJakub Siednienko, Ruaidhri Jackson, Mark Mellett, et al.
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