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European Journal of Medicinal Chemistry|April 20, 2025
Development of potent inhibitors targeting bacterial prolyl-tRNA synthetase through fluorine scanning-directed activity tuningZhiteng Luo, Haipeng Qiu, Xiaoying Peng, et al.Nature Communications|March 13, 2021
Inhibitory mechanism of reveromycin A at the tRNA binding site of a class I synthetaseBingyi Chen, Siting Luo, Songxuan Zhang, et al.Journal of the Science of Food and Agriculture|June 29, 2022
Effects of molecular weight of polyaspartic acid on nitrogen use efficiency and crop yieldTai Liu, Jinhui Yang, Hongyuan Wang, et al.Journal of Medicinal Chemistry|April 1, 2022
Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA SynthetasesZhengjun Cai, Bingyi Chen, Ying Yu, et al.European Journal of Medicinal Chemistry|March 8, 2024
Biochemical and structural characterization of chlorhexidine as an ATP-assisted inhibitor against type 1 methionyl-tRNA synthetase from Gram-positive bacteriaFeihu Lu, Kaijiang Xia, Jingtian Su, et al.European Journal of Medicinal Chemistry|December 11, 2019
Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hoppingJunsong Guo, Bingyi Chen, Ying Yu, et al.Nucleic Acids Research|April 27, 2022
Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetaseJia Yi, Zhengjun Cai, Haipeng Qiu, et al.Nucleic Acids Research|August 14, 2021
X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classificationsYingchen Ju, Lu Han, Bingyi Chen, et al.Nature Communications|September 12, 2022
Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosisDane Huang, Chao Zhao, Ruyue Li, et al.Stem Cell Research & Therapy|March 2, 2025
Apoptotic vesicles derived from bone marrow mesenchymal stem cells increase angiogenesis in a hind limb ischemia model via the NAMPT/SIRT1/FOXO1 axisJinxing Chen, Zekun Shen, Bingyi Chen, et al.Pageof 4