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Current Opinion in Chemical Biology
|
July 23, 2002
Lead discovery using molecular docking
Brian K Shoichet, Susan L McGovern, Binqing Wei, et al.
ACS Medicinal Chemistry Letters
|
January 17, 2024
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
Christian Nilewski, Sharada Labadie, Binqing Wei, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 13, 2019
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity
Shuai Wang, Buyun Chen, Peter Dragovich, et al.
Structure (London, England : 1993)
|
December 4, 2018
Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer
Ping Wu, Christopher J Sneeringer, Keith E Pitts, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
Brian S Safina, Richard L Elliott, Andrew K Forrest, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioconjugate Chemistry
|
September 9, 2017
Attachment Site Cysteine Thiol pK<sub>a</sub> Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates
Breanna S Vollmar, Binqing Wei, Rachana Ohri, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2012
Cis-amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase
Steven T Staben, Nicole Blaquiere, Vickie Tsui, et al.
Journal of Medicinal Chemistry
|
April 4, 2012
Discovery and optimization of a novel spiropyrrolidine inhibitor of β-secretase (BACE1) through fragment-based drug design
Ivan V Efremov, Felix F Vajdos, Kris A Borzilleri, et al.
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of 4
Search research articles
Search
Showing results (1-10 of 40) with videos related to
Sort By:
Page
of 4
Current Opinion in Chemical Biology
|
July 23, 2002
Lead discovery using molecular docking
Brian K Shoichet, Susan L McGovern, Binqing Wei, et al.
ACS Medicinal Chemistry Letters
|
January 17, 2024
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
Christian Nilewski, Sharada Labadie, Binqing Wei, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 13, 2019
A Novel Depurination Methodology to Assess DNA Alkylation of Chloro-Bis-Seco-Cyclopropylbenzoindoles Allowed for Comparison of Minor-Groove Reactivity
Shuai Wang, Buyun Chen, Peter Dragovich, et al.
Structure (London, England : 1993)
|
December 4, 2018
Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer
Ping Wu, Christopher J Sneeringer, Keith E Pitts, et al.
ACS Medicinal Chemistry Letters
|
September 27, 2017
Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles
Brian S Safina, Richard L Elliott, Andrew K Forrest, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioconjugate Chemistry
|
September 9, 2017
Attachment Site Cysteine Thiol pK<sub>a</sub> Is a Key Driver for Site-Dependent Stability of THIOMAB Antibody-Drug Conjugates
Breanna S Vollmar, Binqing Wei, Rachana Ohri, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 23, 2013
Identification of GNE-293, a potent and selective PI3Kδ inhibitor: navigating in vitro genotoxicity while improving potency and selectivity
Brian S Safina, Zachary K Sweeney, Jun Li, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2012
Cis-amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase
Steven T Staben, Nicole Blaquiere, Vickie Tsui, et al.
Journal of Medicinal Chemistry
|
April 4, 2012
Discovery and optimization of a novel spiropyrrolidine inhibitor of β-secretase (BACE1) through fragment-based drug design
Ivan V Efremov, Felix F Vajdos, Kris A Borzilleri, et al.
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of 4